Entity Details

Primary name DYH8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96JB1
EntryNameDYH8_HUMAN
FullNameDynein axonemal heavy chain 8
TaxID9606
Evidenceevidence at protein level
Length4490
SequenceStatuscomplete
DateCreated2007-01-23
DateModified2021-06-02

Ontological Relatives

GenesDNAH8

GO terms

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GOName
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0005858 axonemal dynein complex
GO:0005874 microtubule
GO:0005930 axoneme
GO:0007018 microtubule-based movement
GO:0008569 minus-end-directed microtubule motor activity
GO:0030286 dynein complex
GO:0036126 sperm flagellum
GO:0036157 outer dynein arm
GO:0036158 outer dynein arm assembly
GO:0045505 dynein intermediate chain binding
GO:0051959 dynein light intermediate chain binding
GO:0060285 cilium-dependent cell motility

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR003593 AAA+ ATPase domainDomainDomain
IPR004273 Dynein heavy chain region D6 P-loop domainDomainDomain
IPR013594 Dynein heavy chain, tailDomainDomain
IPR013602 Dynein heavy chain, linkerDomainDomain
IPR024317 Dynein heavy chain, AAA module D4DomainDomain
IPR024743 Dynein heavy chain, coiled coil stalkDomainDomain
IPR026983 Dynein heavy chainFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035699 Dynein heavy chain, hydrolytic ATP-binding dynein motor regionDomainDomain
IPR035706 Dynein heavy chain, ATP-binding dynein motor regionDomainDomain
IPR041228 Dynein heavy chain, C-terminal domainDomainDomain
IPR041466 Dynein heavy chain, AAA 5 extension domainDomainDomain
IPR041589 Dynein heavy chain 3, AAA+ lid domainDomainDomain
IPR041658 Dynein heavy chain AAA lid domainDomainDomain
IPR042219 Dynein heavy chain AAA lid domain superfamilyFamilyHomologous superfamily
IPR042222 Dynein heavy chain, domain 2, N-terminalFamilyHomologous superfamily
IPR042228 Dynein heavy chain, linker, subdomain 3FamilyHomologous superfamily
IPR043157 Dynein heavy chain, AAA1 domain, small subdomainFamilyHomologous superfamily
IPR043160 Dynein heavy chain, C-terminal domain, barrel regionFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DYH8_HUMANGAN_HUMANBioGRID26460568 details