Entity Details

Primary name RHG06_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43182
EntryNameRHG06_HUMAN
FullNameRho GTPase-activating protein 6
TaxID9606
Evidenceevidence at protein level
Length974
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesARHGAP6

GO terms

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GOName
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005884 actin filament
GO:0007202 activation of phospholipase C activity
GO:0007266 Rho protein signal transduction
GO:0010518 positive regulation of phospholipase activity
GO:0015629 actin cytoskeleton
GO:0016004 phospholipase activator activity
GO:0017124 SH3 domain binding
GO:0030041 actin filament polymerization
GO:0043274 phospholipase binding
GO:0043547 positive regulation of GTPase activity
GO:0048041 focal adhesion assembly
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051497 negative regulation of stress fiber assembly
GO:0051895 negative regulation of focal adhesion assembly

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR030772 Rho GTPase-activating protein 6FamilyFamily
IPR037863 Rho GTPase-activating protein 6/36FamilyFamily
IPR041852 ARHGAP6/36, RhoGAP domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
RHG06_HUMANLNX1_HUMANBioGRID22889411 details