Entity Details

Primary name SCAF8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UPN6
EntryNameSCAF8_HUMAN
FullNameSR-related and CTD-associated factor 8
TaxID9606
Evidenceevidence at protein level
Length1271
SequenceStatuscomplete
DateCreated2003-05-09
DateModified2021-06-02

Ontological Relatives

GenesSCAF8

GO terms

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GOName
GO:0000993 RNA polymerase II complex binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005849 mRNA cleavage factor complex
GO:0006369 termination of RNA polymerase II transcription
GO:0006378 mRNA polyadenylation
GO:0016363 nuclear matrix
GO:0032786 positive regulation of DNA-templated transcription, elongation
GO:0043175 RNA polymerase core enzyme binding
GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding
GO:2000805 negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled

Subcellular Location

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Subcellular Location
Nucleus
Nucleus matrix

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR006569 CID domainDomainDomain
IPR008942 ENTH/VHSFamilyHomologous superfamily
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034370 SCAF8, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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