Entity Details

Primary name FOXA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y261
EntryNameFOXA2_HUMAN
FullNameHepatocyte nuclear factor 3-beta
TaxID9606
Evidenceevidence at protein level
Length457
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesFOXA2

GO terms

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GOName
GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001708 cell fate specification
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006325 chromatin organization
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008134 transcription factor binding
GO:0008344 adult locomotory behavior
GO:0009653 anatomical structure morphogenesis
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0019904 protein domain specific binding
GO:0030054 cell junction
GO:0030154 cell differentiation
GO:0030193 regulation of blood coagulation
GO:0031018 endocrine pancreas development
GO:0033132 negative regulation of glucokinase activity
GO:0040019 positive regulation of embryonic development
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0061987 negative regulation of transcription from RNA polymerase II promoter by glucose
GO:0070741 response to interleukin-6
GO:0071542 dopaminergic neuron differentiation
GO:0090009 primitive streak formation
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin
GO:2000543 positive regulation of gastrulation
GO:2000971 negative regulation of detection of glucose

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001766 Fork head domainDomainDomain
IPR013638 Fork-head N-terminalDomainDomain
IPR018122 Fork head domain conserved site1SiteConserved site
IPR018533 Forkhead box protein, C-terminalDomainDomain
IPR030456 Fork head domain conserved site 2SiteConserved site
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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