Entity Details
| Primary name |
LRIG2_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | O94898 |
| EntryName | LRIG2_HUMAN |
| FullName | Leucine-rich repeats and immunoglobulin-like domains protein 2 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 1065 |
| SequenceStatus | complete |
| DateCreated | 2004-10-11 |
| DateModified | 2021-06-02 |
Subcellular Location
Show/Hide Table
| Subcellular Location |
| Cell membrane |
| Cytoplasm |
Domains
Show/Hide Table
| Domain | Name | Category | Type |
| IPR000483 | Cysteine-rich flanking region, C-terminal | Domain | Domain |
| IPR001611 | Leucine-rich repeat | Repeat | Repeat |
| IPR003591 | Leucine-rich repeat, typical subtype | Repeat | Repeat |
| IPR003598 | Immunoglobulin subtype 2 | Domain | Domain |
| IPR003599 | Immunoglobulin subtype | Domain | Domain |
| IPR007110 | Immunoglobulin-like domain | Domain | Domain |
| IPR013098 | Immunoglobulin I-set | Domain | Domain |
| IPR013783 | Immunoglobulin-like fold | Family | Homologous superfamily |
| IPR032675 | Leucine-rich repeat domain superfamily | Family | Homologous superfamily |
| IPR036179 | Immunoglobulin-like domain superfamily | Family | Homologous superfamily |
Diseases
Show/Hide Table
| Disease ID | Source | Name | Description |
| 615112 | OMIM | Urofacial syndrome 2 (UFS2) | A rare autosomal recessive disorder characterized by facial grimacing when attempting to smile and failure of the urinary bladder to void completely despite a lack of anatomical bladder outflow obstruction or overt neurological damage. Affected individuals often have reflux of infected urine from the bladder to the upper renal tract, with a risk of kidney damage and renal failure. The disease is caused by variants affecting the gene represented in this entry. |
Interactions
3 interactions