Entity Details

Primary name LA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP05455
EntryNameLA_HUMAN
FullNameLupus La protein
TaxID9606
Evidenceevidence at protein level
Length408
SequenceStatuscomplete
DateCreated1988-11-01
DateModified2021-06-02

Ontological Relatives

GenesSSB

GO terms

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GOName
GO:0000049 tRNA binding
GO:0000781 chromosome, telomeric region
GO:0001682 tRNA 5'-leader removal
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006400 tRNA modification
GO:0006409 tRNA export from nucleus
GO:0008033 tRNA processing
GO:0008266 poly(U) RNA binding
GO:0008334 histone mRNA metabolic process
GO:0042780 tRNA 3'-end processing
GO:0071045 nuclear histone mRNA catabolic process
GO:0075522 IRES-dependent viral translational initiation
GO:1903608 protein localization to cytoplasmic stress granule
GO:1990825 sequence-specific mRNA binding
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR002344 Lupus La proteinFamilyFamily
IPR006630 La-type HTH domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR014886 La protein, xRRM domainDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

34 interactions

InteractorPartnerSourcesPublicationsLink
LA_HUMANHMGA1_HUMANBioGRID, IntAct18850631 details
LA_HUMANSPIB_HUMANBioGRID, IntAct21988832 details
LA_HUMANCSK21_HUMANBioGRID, IntAct19039329 22113938 details
LA_HUMANHSP72_HUMANIntAct32814053 details
LA_HUMANNDUBA_HUMANIntAct32814053 details
LA_HUMANRPGF4_HUMANIntAct32814053 details
LA_HUMANHD_HUMANIntAct32814053 details
LA_HUMANOSTP_HUMANBioGRID22779921 details
LA_HUMANA4_HUMANBioGRID21832049 details
LA_HUMANGRAH_HUMANBioGRID19039329 details
LA_HUMANCSK2B_HUMANBioGRID19039329 details
LA_HUMANPTEN_HUMANBioGRID31685992 details
LA_HUMANCDC42_HUMANBioGRID31478661 details
LA_HUMANOGT1_HUMANBioGRID32994395 details
LA_HUMANM3K14_HUMANIntAct14743216 details
LA_HUMANTRAF6_HUMANIntAct17353931 details
LA_HUMANLYAR_HUMANIntAct17353931 details
LA_HUMANAAKB1_HUMANIntAct17353931 details
LA_HUMANTNR14_HUMANIntAct17353931 details
LA_HUMANNDKB_HUMANIntAct17353931 details
LA_HUMANVHL_HUMANIntAct17353931 details
LA_HUMANIKKE_HUMANIntAct17353931 details
LA_HUMAN1433Z_HUMANMINT15161933 details
LA_HUMANGCR_HUMANIntAct20195357 details
LA_HUMANSCHI1_HUMANIntAct20195357 details
LA_HUMANRXRB_HUMANIntAct20195357 details
LA_HUMANPRP31_HUMANBioGRID, IntAct27173435 unassigned1312 details
LA_HUMANNUCL_HUMANBioGRID, DIP, HPRD12096904 18292223 details
LA_HUMANH2AX_HUMANBioGRID16522924 details
LA_HUMANEMD_HUMANBioGRID17620012 details
LA_HUMANRO60_HUMANBioGRID10785401 details
LA_HUMANATOH1_HUMANBioGRID27542412 details
LA_HUMANEIF3H_HUMANBioGRID32269044 details
LA_HUMANLA_HUMANHPRD15485924 details