Entity Details

Primary name NID1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP14543
EntryNameNID1_HUMAN
FullNameNidogen-1
TaxID9606
Evidenceevidence at protein level
Length1247
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesNID1

GO terms

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GOName
GO:0005201 extracellular matrix structural constituent
GO:0005509 calcium ion binding
GO:0005518 collagen binding
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005886 plasma membrane
GO:0007160 cell-matrix adhesion
GO:0010811 positive regulation of cell-substrate adhesion
GO:0030198 extracellular matrix organization
GO:0032836 glomerular basement membrane development
GO:0043236 laminin binding
GO:0043237 laminin-1 binding
GO:0043394 proteoglycan binding
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0071711 basement membrane organization

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000033 LDLR class B repeatRepeatRepeat
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000716 Thyroglobulin type-1DomainDomain
IPR000742 EGF-like domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR003886 NIDO domainDomainDomain
IPR006605 G2 nidogen/fibulin G2FDomainDomain
IPR009017 Green fluorescent proteinFamilyHomologous superfamily
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR011042 Six-bladed beta-propeller, TolB-likeFamilyHomologous superfamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR024731 EGF domainDomainDomain
IPR026823 Complement Clr-like EGF domainDomainDomain
IPR036857 Thyroglobulin type-1 superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00013 UrokinaseDrugbankbiotech