Entity Details

Primary name M3K9_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP80192
EntryNameM3K9_HUMAN
FullNameMitogen-activated protein kinase kinase kinase 9
TaxID9606
Evidenceevidence at protein level
Length1104
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesMAP3K9

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004706 JUN kinase kinase kinase activity
GO:0004708 MAP kinase kinase activity
GO:0005524 ATP binding
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0007257 obsolete activation of JUN kinase activity
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0046777 protein autophosphorylation
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR016231 Mitogen-activated protein (MAP) kinase kinase kinase, MLK1-4FamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR035779 MLK1-3, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB08703 12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-oneDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule