Entity Details

Primary name SRSF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01130
EntryNameSRSF2_HUMAN
FullNameSerine/arginine-rich splicing factor 2
TaxID9606
Evidenceevidence at protein level
Length221
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesSRSF2

GO terms

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GOName
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000398 mRNA splicing, via spliceosome
GO:0003714 transcription corepressor activity
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006397 mRNA processing
GO:0006405 RNA export from nucleus
GO:0006406 mRNA export from nucleus
GO:0008380 RNA splicing
GO:0016607 nuclear speck
GO:0031124 mRNA 3'-end processing

Subcellular Location

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Subcellular Location
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR003954 RNA recognition motif domain, eukaryoteDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034893 Serine/arginine-rich splicing factor 2-likeFamilyFamily
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

59 interactions

InteractorPartnerSourcesPublicationsLink
SRSF2_HUMANCIR1_HUMANBioGRID, HPRD, IntAct15652350 3031469 details
SRSF2_HUMANUBQL4_HUMANBioGRID, HPRD, IntAct16713569 details
SRSF2_HUMANKAT5_HUMANBioGRID, MINT21157427 details
SRSF2_HUMANCDK6_HUMANBioGRID, IntAct22094256 details
SRSF2_HUMANCSK21_HUMANBioGRID, IntAct22113938 details
SRSF2_HUMANU2AF1_HUMANBioGRID, HPRD, MINT, UniProt18559666 22365833 8261509 8816452 details
SRSF2_HUMANSRSF3_HUMANBioGRID, MINT22365833 details
SRSF2_HUMANSRSF4_HUMANBioGRID, MINT22365833 details
SRSF2_HUMANSRSF2_HUMANBioGRID, MINT22365833 details
SRSF2_HUMANTRA2B_HUMANBioGRID, MINT22365833 details
SRSF2_HUMANSRPK2_HUMANBioGRID, IntAct19592491 23602568 9472028 details
SRSF2_HUMANCCNL1_HUMANHPRD, IntAct11683997 18216018 details
SRSF2_HUMANPAK1_HUMANDIP17389360 details
SRSF2_HUMANRU17_HUMANBioGRID, HPRD, UniProt18559666 29802200 8261509 details
SRSF2_HUMANSRSF1_HUMANBioGRID26344197 8816452 details
SRSF2_HUMANSRS11_HUMANBioGRID, HPRD8816452 details
SRSF2_HUMANU2AF5_HUMANBioGRID, HPRD22365833 8261509 8816452 details
SRSF2_HUMANSREK1_HUMANBioGRID, HPRD10757789 11991645 14559993 details
SRSF2_HUMANNCF1_HUMANBioGRID, HPRD16052631 details
SRSF2_HUMANBARD1_HUMANBioGRID22990118 details
SRSF2_HUMANDNLI4_HUMANBioGRID22990118 details
SRSF2_HUMANPAXI1_HUMANBioGRID22990118 details
SRSF2_HUMANGOGA2_HUMANBioGRID25416956 details
SRSF2_HUMANK1H1_HUMANBioGRID25416956 details
SRSF2_HUMANTRI27_HUMANBioGRID25416956 details
SRSF2_HUMANITF2_HUMANBioGRID25416956 details
SRSF2_HUMANCEP72_HUMANBioGRID25416956 details
SRSF2_HUMANLZTS2_HUMANBioGRID25416956 details
SRSF2_HUMANK1C40_HUMANBioGRID25416956 details
SRSF2_HUMANU2AFM_HUMANHPRD9237760 details
SRSF2_HUMANGEMI2_HUMANHPRD9447963 details
SRSF2_HUMANSCAFB_HUMANHPRD9447963 details
SRSF2_HUMANYTDC1_HUMANHPRD9473574 details
SRSF2_HUMANFUS_HUMANHPRD9774382 details
SRSF2_HUMANSF3A2_HUMANBioGRID, MINT17332742 details
SRSF2_HUMANPDIP3_HUMANIntAct18423201 details
SRSF2_HUMANHABP4_HUMANMINT19523114 details
SRSF2_HUMANAIRE_HUMANBioGRID, IntAct20085707 details
SRSF2_HUMANHNRPM_HUMANMINT20467437 details
SRSF2_HUMANHDAC6_HUMANMINT21157427 details
SRSF2_HUMANSDCG8_HUMANIntAct22863007 details
SRSF2_HUMANCE164_HUMANBioGRID, IntAct22863007 26638075 details
SRSF2_HUMANZN423_HUMANIntAct22863007 details
SRSF2_HUMANCHK1_HUMANIntAct22863007 details
SRSF2_HUMANNUCL_HUMANMINT23353999 details
SRSF2_HUMANCHTOP_HUMANMINT23299939 details
SRSF2_HUMANCCNL2_HUMANHPRD, IntAct14684736 18216018 details
SRSF2_HUMANDEK_HUMANBioGRID10908574 details
SRSF2_HUMANPRGC1_HUMANBioGRID10983978 details
SRSF2_HUMANCDC5L_HUMANBioGRID11101529 details
SRSF2_HUMANSRRM1_HUMANBioGRID16159877 details
SRSF2_HUMANTHOC4_HUMANBioGRID15998806 details
SRSF2_HUMANNXF1_HUMANBioGRID15184380 details
SRSF2_HUMANU2AF2_HUMANBioGRID22939629 26641092 details
SRSF2_HUMAN1433E_HUMANBioGRID19608861 details
SRSF2_HUMANZRAB2_HUMANHPRD11448987 details
SRSF2_HUMANADAP1_HUMANHPRD12565890 details
SRSF2_HUMANCDK12_HUMANHPRD11683387 details
SRSF2_HUMANPRCC_HUMANHPRD11313942 details