Entity Details

Primary name GUC2D_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ02846
EntryNameGUC2D_HUMAN
FullNameRetinal guanylyl cyclase 1
TaxID9606
Evidenceevidence at protein level
Length1103
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesGUCY2D

GO terms

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GOName
GO:0001653 peptide receptor activity
GO:0001750 photoreceptor outer segment
GO:0004383 guanylate cyclase activity
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005640 nuclear outer membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006182 cGMP biosynthetic process
GO:0007165 signal transduction
GO:0007168 receptor guanylyl cyclase signaling pathway
GO:0007601 visual perception
GO:0022400 regulation of rhodopsin mediated signaling pathway
GO:0035556 intracellular signal transduction
GO:0038023 signaling receptor activity
GO:0042622 photoreceptor outer segment membrane
GO:0042803 protein homodimerization activity
GO:0097381 photoreceptor disc membrane

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Photoreceptor outer segment membrane

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclaseDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001828 Receptor, ligand binding regionDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011645 Haem NO binding associatedDomainDomain
IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved siteSiteConserved site
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily
IPR029787 Nucleotide cyclaseFamilyHomologous superfamily

Diseases

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