Entity Details

Primary name PTPS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ03393
EntryNamePTPS_HUMAN
FullName6-pyruvoyl tetrahydrobiopterin synthase
TaxID9606
Evidenceevidence at protein level
Length145
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesPTS

GO terms

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GOName
GO:0003874 6-pyruvoyltetrahydropterin synthase activity
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006520 cellular amino acid metabolic process
GO:0006729 tetrahydrobiopterin biosynthetic process
GO:0007417 central nervous system development
GO:0042802 identical protein binding
GO:0046146 tetrahydrobiopterin metabolic process
GO:0046872 metal ion binding

Subcellular Location

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Domains

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DomainNameCategoryType
IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD familyFamilyFamily
IPR022469 6-pyruvoyl tetrahydropterin synthase, histidine active siteSiteActive site
IPR022470 6-pyruvoyl tetrahydropterin synthase, cysteine active siteSiteActive site
IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00688 Mycophenolate mofetilDrugbanksmall molecule
DB03886 BiopterinDrugbanksmall molecule