Entity Details

Primary name MYO7A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13402
EntryNameMYO7A_HUMAN
FullNameUnconventional myosin-VIIa
TaxID9606
Evidenceevidence at protein level
Length2215
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesMYO7A

GO terms

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GOName
GO:0000146 microfilament motor activity
GO:0001750 photoreceptor outer segment
GO:0001845 phagolysosome assembly
GO:0001917 photoreceptor inner segment
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005902 microvillus
GO:0005938 cell cortex
GO:0006886 intracellular protein transport
GO:0007015 actin filament organization
GO:0007040 lysosome organization
GO:0007423 sensory organ development
GO:0007601 visual perception
GO:0007605 sensory perception of sound
GO:0015629 actin cytoskeleton
GO:0016324 apical plasma membrane
GO:0019904 protein domain specific binding
GO:0030048 actin filament-based movement
GO:0030050 vesicle transport along actin filament
GO:0030507 spectrin binding
GO:0031477 myosin VII complex
GO:0031982 vesicle
GO:0032391 photoreceptor connecting cilium
GO:0032420 stereocilium
GO:0034613 cellular protein localization
GO:0042462 eye photoreceptor cell development
GO:0042470 melanosome
GO:0042490 mechanoreceptor differentiation
GO:0042802 identical protein binding
GO:0043531 ADP binding
GO:0045202 synapse
GO:0047485 protein N-terminus binding
GO:0048563 post-embryonic animal organ morphogenesis
GO:0050953 sensory perception of light stimulus
GO:0050957 equilibrioception
GO:0051015 actin filament binding
GO:0051904 pigment granule transport
GO:0060088 auditory receptor cell stereocilium organization
GO:0120044 stereocilium base
GO:1990435 upper tip-link density

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm

Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR000299 FERM domainDomainDomain
IPR000857 MyTH4 domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001609 Myosin head, motor domainDomainDomain
IPR008989 Myosin S1 fragment, N-terminalFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036106 Class VII myosin, motor domainDomainDomain
IPR036961 Kinesin motor domain superfamilyFamilyHomologous superfamily
IPR038185 MyTH4 domain superfamilyFamilyHomologous superfamily
IPR041793 Myosin VII, FERM domain C-lobe, repeat 1DomainDomain
IPR041794 Myosin VII, FERM domain C-lobe, repeat 2DomainDomain

Diseases

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