Entity Details

Primary name DIS3
Entity type gene
Source Source Link

Details

PrimaryID22894
RefseqGene
SymbolDIS3
NameDIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
Chromosome13
Location13q21.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsRRP44_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000176 nuclear exosome (RNase complex)
GO:0000177 cytoplasmic exosome (RNase complex)
GO:0000178 exosome (RNase complex)
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006364 rRNA processing
GO:0016020 membrane
GO:0016075 rRNA catabolic process
GO:0043488 regulation of mRNA stability
GO:0043928 exonucleolytic catabolism of deadenylated mRNA
GO:0071034 CUT catabolic process

Diseases

Show/Hide Table

Interactions

110 interactions

InteractorPartnerSourcesPublicationsLink
DIS3EXOSC10BioGRID, HPRD, IntAct, MINT15231747 20531386 21255825 23756462 26344197 details
DIS3EXOSC8BioGRID, HPRD, IntAct, MINT11719186 15231747 20531386 details
DIS3NTMT1BioGRID, IntAct15231747 details
DIS3ZBTB17BioGRID, HPRD, IntAct15231747 details
DIS3EXOSC9BioGRID, HPRD, MINT11719186 12788944 20531386 26344197 details
DIS3NME2IntAct17353931 details
DIS3NME1-NME2IntAct17353931 details
DIS3EXOSC3BioGRID, IntAct, MINT20531386 20531389 21255825 details
DIS3EXOSC5BioGRID, HPRD, MINT11719186 20531386 details
DIS3EXOSC4BioGRID, HPRD, MINT11719186 20531386 26344197 details
DIS3EXOSC7BioGRID, HPRD, MINT11719186 20531386 26344197 details
DIS3EXOSC2BioGRID, HPRD, MINT11719186 20531386 26344197 details
DIS3COPZ1BioGRID, IntAct27173435 unassigned1312 details
DIS3SARNPBioGRID, IntAct27173435 unassigned1312 details
DIS3CDK5BioGRID, IntAct27173435 unassigned1312 details
DIS3SEPTIN7BioGRID, IntAct27173435 unassigned1312 details
DIS3SCYL2BioGRID, IntAct27173435 unassigned1312 details
DIS3PRCCBioGRID, IntAct27173435 unassigned1312 details
DIS3SEPTIN11BioGRID, IntAct27173435 unassigned1312 details
DIS3CHORDC1BioGRID, IntAct27173435 unassigned1312 details
DIS3DRG1BioGRID, IntAct27173435 unassigned1312 details
DIS3SUB1BioGRID, IntAct27173435 unassigned1312 details
DIS3SH3GLB1BioGRID, IntAct27173435 unassigned1312 details
DIS3DISC1IntAct31413325 details
DIS3MTREXBioGRID, HPRD11719186 20531386 details
DIS3AICDABioGRID21255825 details
DIS3RNF126BioGRID26508657 details
DIS3TULP3BioGRID33187986 details
DIS3PALS2HPRD11719186 details
DIS3EXOSC6HPRD11719186 details
DIS3BABAM1BioGRID, IntAct19615732 details
DIS3EXOSC1BioGRID, MINT20531386 details
DIS3CUL3BioGRID, IntAct21145461 details
DIS3CUL5BioGRID, IntAct21145461 details
DIS3DIS3MINT23756462 details
DIS3LRRK2IntAct24725412 31046837 details
DIS3JUNMINT25609649 details
DIS3SORT1BioGRID, IntAct26496610 details
DIS3HSCBBioGRID, IntAct28380382 details
DIS3GTF2E2BioGRID, IntAct28514442 details
DIS3SNRNP27BioGRID, IntAct28514442 details
DIS3FGBBioGRID, IntAct28514442 details
DIS3SERPINB2BioGRID, IntAct28514442 details
DIS3DCXBioGRID, IntAct26186194 28514442 details
DIS3YJU2BioGRID, IntAct28514442 details
DIS3C1DBioGRID, IntAct28514442 details
DIS3IQCF1BioGRID, IntAct28514442 details
DIS3EID3BioGRID, IntAct28514442 details
DIS3CYP1A1BioGRID, IntAct26186194 28514442 details
DIS3GAS2L1BioGRID, IntAct26186194 28514442 details
DIS3MUS81BioGRID, IntAct28514442 details
DIS3NELFEBioGRID, IntAct26186194 28514442 details
DIS3RBM23BioGRID, IntAct26186194 28514442 details
DIS3SSBP3BioGRID, IntAct26186194 28514442 details
DIS3ZNF212BioGRID, IntAct28514442 details
DIS3DLX4BioGRID, IntAct28514442 details
DIS3RRP1BIntAct20926688 details
DIS3TP53BP1BioGRID, UniProt29656893 details
DIS3AHNAKBioGRID, IntAct30021884 details
DIS3PLECBioGRID, IntAct30021884 details
DIS3BCL2L14BioGRID, IntAct30833792 details
DIS3SH2D3CBioGRID, IntAct31980649 details
DIS3SIRT7BioGRID22586326 details
DIS3PPP5CBioGRID22939629 details
DIS3SH3PXD2BBioGRID22939629 details
DIS3WDR1BioGRID22939629 details
DIS3STXBP3BioGRID22939629 details
DIS3TWF1BioGRID22863883 details
DIS3EGFRBioGRID24797263 details
DIS3NMD3BioGRID26344197 details
DIS3RCC1BioGRID26344197 details
DIS3GNASBioGRID26344197 details
DIS3KPNB1BioGRID26344197 details
DIS3RANBioGRID26344197 details
DIS3RAVER1BioGRID26344197 details
DIS3SEPHS1BioGRID26344197 details
DIS3NTRK1BioGRID25921289 details
DIS3TESBioGRID28378594 details
DIS3TRIM14BioGRID29053956 details
DIS3MAPK6BioGRID26972000 details
DIS3BMPR1ABioGRID27684187 details
DIS3EFTUD2BioGRID28515276 details
DIS3SOCS2BioGRID28883622 details
DIS3SOCS6BioGRID28883622 details
DIS3CDC34BioGRID29564676 details
DIS3WWOXBioGRID30619736 details
DIS3TXNIPBioGRID29378950 details
DIS3MYCBioGRID29467282 details
DIS3ATG16L1BioGRID30196744 details
DIS3PHBBioGRID27025967 details
DIS3NR2C2BioGRID30463901 details
DIS3DUSP22BioGRID28675297 details
DIS3ITFG1BioGRID25437307 details
DIS3BIRC3BioGRID30948266 details
DIS3STAU1BioGRID30948266 details
DIS3PLEKHA4BioGRID31091453 details
DIS3PINK1BioGRID31300519 details
DIS3RBM45BioGRID26979993 details
DIS3BRD4BioGRID32416067 details
DIS3UBR5BioGRID32867711 details
DIS3RBM39BioGRID28302793 details
DIS3KDF1BioGRID32239614 details
DIS3MARCHF6BioGRID32614325 details
DIS3RNF103BioGRID32614325 details
DIS3RNF185BioGRID32614325 details
DIS3TMEM129BioGRID32614325 details
DIS3CD274BioGRID32941674 details
DIS3DDRGK1BioGRID32807901 details
DIS3TP53BioGRID32807901 details
DIS3DDX58BioGRID32513696 details