Entity Details

Primary name ACOX1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15067
EntryNameACOX1_HUMAN
FullNamePeroxisomal acyl-coenzyme A oxidase 1
TaxID9606
Evidenceevidence at protein level
Length660
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesACOX1

GO terms

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GOName
GO:0000038 very long-chain fatty acid metabolic process
GO:0003997 acyl-CoA oxidase activity
GO:0005504 fatty acid binding
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005782 peroxisomal matrix
GO:0005829 cytosol
GO:0006091 generation of precursor metabolites and energy
GO:0006629 lipid metabolic process
GO:0006693 prostaglandin metabolic process
GO:0007283 spermatogenesis
GO:0008104 protein localization
GO:0009062 fatty acid catabolic process
GO:0016020 membrane
GO:0016401 palmitoyl-CoA oxidase activity
GO:0016559 peroxisome fission
GO:0019222 regulation of metabolic process
GO:0019395 fatty acid oxidation
GO:0030165 PDZ domain binding
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase
GO:0036109 alpha-linolenic acid metabolic process
GO:0042632 cholesterol homeostasis
GO:0042803 protein homodimerization activity
GO:0047485 protein N-terminus binding
GO:0050660 flavin adenine dinucleotide binding
GO:0050665 hydrogen peroxide biosynthetic process
GO:0055088 lipid homeostasis
GO:0071949 FAD binding
GO:0140493 very long-chain fatty acid beta-oxidation

Subcellular Location

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Subcellular Location
Peroxisome

Domains

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DomainNameCategoryType
IPR002655 Acyl-CoA oxidase, C-terminalDomainDomain
IPR006091 Acyl-CoA oxidase/dehydrogenase, central domainDomainDomain
IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamilyFamilyHomologous superfamily
IPR012258 Acyl-CoA oxidaseFamilyFamily
IPR029320 Acyl-coenzyme A oxidase, N-terminalDomainDomain
IPR034171 Peroxisomal acyl-coenzyme A oxidaseFamilyFamily
IPR036250 Acyl-CoA dehydrogenase-like, C-terminalFamilyHomologous superfamily
IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03147 Flavin adenine dinucleotideDrugbanksmall molecule
DB07930 (3R)-3-HYDROXYDODECANOIC ACIDDrugbanksmall molecule
DB09328 VayarinSwissprotbiotech