Entity Details

Primary name LIRA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N149
EntryNameLIRA2_HUMAN
FullNameLeukocyte immunoglobulin-like receptor subfamily A member 2
TaxID9606
Evidenceevidence at protein level
Length483
SequenceStatuscomplete
DateCreated2003-10-03
DateModified2021-06-02

Ontological Relatives

GenesLILRA2

GO terms

Show/Hide Table
GOName
GO:0001791 IgM binding
GO:0002220 innate immune response activating cell surface receptor signaling pathway
GO:0002283 neutrophil activation involved in immune response
GO:0003823 antigen binding
GO:0005576 extracellular region
GO:0005887 integral component of plasma membrane
GO:0006952 defense response
GO:0007165 signal transduction
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway
GO:0038023 signaling receptor activity
GO:0045087 innate immune response
GO:0050867 positive regulation of cell activation
GO:0051928 positive regulation of calcium ion transport
GO:0071657 positive regulation of granulocyte colony-stimulating factor production

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013151 ImmunoglobulinDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016332 Alpha-1B-glycoprotein/leukocyte immunoglobulin-like receptorFamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink