Entity Details

Primary name 5HT3C_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WXA8
EntryName5HT3C_HUMAN
FullName5-hydroxytryptamine receptor 3C
TaxID9606
Evidenceevidence at protein level
Length447
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesHTR3C

GO terms

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GOName
GO:0004888 transmembrane signaling receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0022850 serotonin-gated cation-selective channel activity
GO:0030594 neurotransmitter receptor activity
GO:0034220 ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0043005 neuron projection
GO:0045202 synapse
GO:0050877 nervous system process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00246 ZiprasidoneDrugbanksmall molecule
DB00715 ParoxetineDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB01049 Ergoloid mesylateDrugbanksmall molecule
DB01239 ChlorprothixeneDrugbanksmall molecule
DB09304 SetiptilineDrugbanksmall molecule
DB11273 DihydroergocornineDrugbanksmall molecule
DB12141 GilteritinibDrugbanksmall molecule
DB13025 TiaprideDrugbanksmall molecule
DB13345 DihydroergocristineDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
5HT3C_HUMAN5HT3A_HUMANIntAct17392525 details