Entity Details

Primary name I22R2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ969J5
EntryNameI22R2_HUMAN
FullNameInterleukin-22 receptor subunit alpha-2
TaxID9606
Evidenceevidence at protein level
Length263
SequenceStatuscomplete
DateCreated2005-03-15
DateModified2021-06-02

Ontological Relatives

GenesIL22RA2

GO terms

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GOName
GO:0004896 cytokine receptor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0042017 interleukin-22 binding
GO:0042018 interleukin-22 receptor activity
GO:0042509 regulation of tyrosine phosphorylation of STAT protein
GO:0050728 negative regulation of inflammatory response

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015373 Interferon/interleukin receptor domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
I22R2_HUMANIL22_HUMANBioGRID, DIP, HPRD, MINT11390453 18599299 19285080 details