Entity Details

Primary name ABCD4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14678
EntryNameABCD4_HUMAN
FullNameLysosomal cobalamin transporter ABCD4
TaxID9606
Evidenceevidence at protein level
Length606
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesABCD4

GO terms

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GOName
GO:0005324 long-chain fatty acid transporter activity
GO:0005524 ATP binding
GO:0005765 lysosomal membrane
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005789 endoplasmic reticulum membrane
GO:0006635 fatty acid beta-oxidation
GO:0007031 peroxisome organization
GO:0009235 cobalamin metabolic process
GO:0015910 long-chain fatty acid import into peroxisome
GO:0016021 integral component of membrane
GO:0016887 ATP hydrolysis activity
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042760 very long-chain fatty acid catabolic process
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055085 transmembrane transport
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Lysosome membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR011527 ABC transporter type 1, transmembrane domainDomainDomain
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036640 ABC transporter type 1, transmembrane domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

6 interactions