Entity Details

Primary name SPIT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43291
EntryNameSPIT2_HUMAN
FullNameKunitz-type protease inhibitor 2
TaxID9606
Evidenceevidence at protein level
Length252
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesSPINT2

GO terms

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GOName
GO:0001843 neural tube closure
GO:0004866 endopeptidase inhibitor activity
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007163 establishment or maintenance of cell polarity
GO:0016021 integral component of membrane
GO:0022408 negative regulation of cell-cell adhesion
GO:0060672 epithelial cell morphogenesis involved in placental branching
GO:0071711 basement membrane organization
GO:0071773 cellular response to BMP stimulus
GO:2000146 negative regulation of cell motility
GO:2000178 negative regulation of neural precursor cell proliferation

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002223 Pancreatic trypsin inhibitor Kunitz domainDomainDomain
IPR020901 Proteinase inhibitor I2, Kunitz, conserved siteSiteConserved site
IPR036880 Pancreatic trypsin inhibitor Kunitz domain superfamilyFamilyHomologous superfamily

Diseases

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