Entity Details
| Primary name |
ISK1_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | P00995 |
| EntryName | ISK1_HUMAN |
| FullName | Serine protease inhibitor Kazal-type 1 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 79 |
| SequenceStatus | complete |
| DateCreated | 1986-07-21 |
| DateModified | 2021-06-02 |
GO terms
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| GO | Name |
| GO:0004866 | endopeptidase inhibitor activity |
| GO:0004867 | serine-type endopeptidase inhibitor activity |
| GO:0010751 | negative regulation of nitric oxide mediated signal transduction |
| GO:0048240 | sperm capacitation |
| GO:0050732 | negative regulation of peptidyl-tyrosine phosphorylation |
| GO:0060046 | regulation of acrosome reaction |
| GO:0070062 | extracellular exosome |
| GO:0090281 | negative regulation of calcium ion import |
| GO:1900004 | negative regulation of serine-type endopeptidase activity |
| GO:2001256 | regulation of store-operated calcium entry |
Subcellular Location
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| Subcellular Location |
| Secreted |
Domains
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| Domain | Name | Category | Type |
| IPR001239 | Proteinase inhibitor I1, Kazal-type, metazoa | Family | Family |
| IPR002350 | Kazal domain | Domain | Domain |
| IPR036058 | Kazal domain superfamily | Family | Homologous superfamily |
Interactions
6 interactions