Entity Details

Primary name MT1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP04731
EntryNameMT1A_HUMAN
FullNameMetallothionein-1A
TaxID9606
Evidenceevidence at protein level
Length61
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesMT1A

GO terms

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GOName
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006882 cellular zinc ion homeostasis
GO:0008270 zinc ion binding
GO:0010038 response to metal ion
GO:0010273 detoxification of copper ion
GO:0045926 negative regulation of growth
GO:0046872 metal ion binding
GO:0071276 cellular response to cadmium ion
GO:0071280 cellular response to copper ion
GO:0071294 cellular response to zinc ion

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000006 Metallothionein, vertebrateFamilyFamily
IPR003019 MetallothioneinFamilyFamily
IPR017854 Metallothionein domain superfamilyFamilyHomologous superfamily
IPR018064 Metallothionein, vertebrate, metal binding siteSiteBinding site
IPR023587 Metallothionein domain superfamily, vertebrateFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00435 Nitric OxideDrugbanksmall molecule
DB00515 CisplatinDrugbanksmall molecule
DB00526 OxaliplatinSwissprotsmall molecule
DB00958 CarboplatinSwissprotsmall molecule
DB01593 ZincDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB12965 SilverDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule