Entity Details

Primary name ADH1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP07327
EntryNameADH1A_HUMAN
FullNameAlcohol dehydrogenase 1A
TaxID9606
Evidenceevidence at protein level
Length375
SequenceStatuscomplete
DateCreated1988-04-01
DateModified2021-06-02

Ontological Relatives

GenesADH1A

GO terms

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GOName
GO:0004024 alcohol dehydrogenase activity, zinc-dependent
GO:0004745 NAD-retinol dehydrogenase activity
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006066 alcohol metabolic process
GO:0006069 ethanol oxidation
GO:0008270 zinc ion binding
GO:0017144 drug metabolic process
GO:0042572 retinol metabolic process
GO:0042573 retinoic acid metabolic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002328 Alcohol dehydrogenase, zinc-type, conserved siteSiteConserved site
IPR011032 GroES-like superfamilyFamilyHomologous superfamily
IPR013149 Alcohol dehydrogenase, C-terminalDomainDomain
IPR013154 Alcohol dehydrogenase, N-terminalDomainDomain
IPR020843 Polyketide synthase, enoylreductase domainDomainDomain
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB01213 FomepizoleDrugbanksmall molecule
DB02721 4-IodopyrazoleDrugbanksmall molecule
DB04065 N-Cyclopentyl-N-CyclobutylformamideDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ADH1A_HUMANHCDH_HUMANBioGRID, IntAct21988832 details
ADH1A_HUMANCSK22_HUMANBioGRID, IntAct21988832 details
ADH1A_HUMANADH1A_HUMANHPRD9982 details