Entity Details

Primary name PERE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11678
EntryNamePERE_HUMAN
FullNameEosinophil peroxidase
TaxID9606
Evidenceevidence at protein level
Length715
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesEPX

GO terms

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GOName
GO:0002215 defense response to nematode
GO:0004601 peroxidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006979 response to oxidative stress
GO:0020037 heme binding
GO:0032693 negative regulation of interleukin-10 production
GO:0032714 negative regulation of interleukin-5 production
GO:0032753 positive regulation of interleukin-4 production
GO:0034774 secretory granule lumen
GO:0042742 defense response to bacterium
GO:0042744 hydrogen peroxide catabolic process
GO:0043312 neutrophil degranulation
GO:0046872 metal ion binding
GO:0070062 extracellular exosome
GO:0072677 eosinophil migration

Subcellular Location

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Subcellular Location
Cytoplasmic granule

Domains

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DomainNameCategoryType
IPR010255 Haem peroxidase superfamilyFamilyHomologous superfamily
IPR019791 Haem peroxidase, animal-typeFamilyFamily
IPR029599 Eosinophil peroxidaseFamilyFamily
IPR037120 Haem peroxidase domain superfamily, animal typeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01065 MelatoninDrugbanksmall molecule

Interactions

4 interactions