Entity Details

Primary name ACHB3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ05901
EntryNameACHB3_HUMAN
FullNameNeuronal acetylcholine receptor subunit beta-3
TaxID9606
Evidenceevidence at transcript level
Length458
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesCHRNB3

GO terms

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GOName
GO:0004888 transmembrane signaling receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005892 acetylcholine-gated channel complex
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0007271 synaptic transmission, cholinergic
GO:0015267 channel activity
GO:0016021 integral component of membrane
GO:0022848 acetylcholine-gated cation-selective channel activity
GO:0030594 neurotransmitter receptor activity
GO:0034220 ion transmembrane transport
GO:0035094 response to nicotine
GO:0042166 acetylcholine binding
GO:0042391 regulation of membrane potential
GO:0043005 neuron projection
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0050877 nervous system process

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR002394 Nicotinic acetylcholine receptorFamilyFamily
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00184 NicotineDrugbanksmall molecule
DB00237 ButabarbitalDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink