Entity Details

Primary name IL33_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BVZ5
EntryNameIL33_MOUSE
FullNameInterleukin-33
TaxID10090
Evidenceevidence at protein level
Length266
SequenceStatuscomplete
DateCreated2005-07-05
DateModified2021-06-02

Ontological Relatives

GenesIl33

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001819 positive regulation of cytokine production
GO:0002112 interleukin-33 receptor binding
GO:0002281 macrophage activation involved in immune response
GO:0002282 microglial cell activation involved in immune response
GO:0002638 negative regulation of immunoglobulin production
GO:0002639 positive regulation of immunoglobulin production
GO:0002686 negative regulation of leukocyte migration
GO:0002826 negative regulation of T-helper 1 type immune response
GO:0002830 positive regulation of type 2 immune response
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0010186 positive regulation of cellular defense response
GO:0010628 positive regulation of gene expression
GO:0030133 transport vesicle
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032689 negative regulation of interferon-gamma production
GO:0032722 positive regulation of chemokine production
GO:0032736 positive regulation of interleukin-13 production
GO:0032753 positive regulation of interleukin-4 production
GO:0032754 positive regulation of interleukin-5 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0038172 interleukin-33-mediated signaling pathway
GO:0043032 positive regulation of macrophage activation
GO:0043231 intracellular membrane-bounded organelle
GO:0045345 positive regulation of MHC class I biosynthetic process
GO:0045348 positive regulation of MHC class II biosynthetic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0050729 positive regulation of inflammatory response
GO:0051607 defense response to virus
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
GO:0051930 regulation of sensory perception of pain
GO:0061518 microglial cell proliferation
GO:0097191 extrinsic apoptotic signaling pathway
GO:0120042 negative regulation of macrophage proliferation
GO:0150142 positive regulation of CD86 production
GO:0150145 positive regulation of CD80 production

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Cytoplasmic vesicle
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR026145 Interleukin-33FamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
IL33_MOUSEILRL1_MOUSEBioGRID, UniProt17623648 17675517 details