Entity Details

Primary name KDM4A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BW72
EntryNameKDM4A_MOUSE
FullNameLysine-specific demethylase 4A
TaxID10090
Evidenceevidence at protein level
Length1064
SequenceStatuscomplete
DateCreated2004-02-16
DateModified2021-06-02

Ontological Relatives

GenesKdm4a

GO terms

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GOName
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005721 pericentric heterochromatin
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006338 chromatin remodeling
GO:0008270 zinc ion binding
GO:0010507 negative regulation of autophagy
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0014898 cardiac muscle hypertrophy in response to stress
GO:0016577 histone demethylation
GO:0031625 ubiquitin protein ligase binding
GO:0031667 response to nutrient levels
GO:0032452 histone demethylase activity
GO:0032454 histone demethylase activity (H3-K9 specific)
GO:0033169 histone H3-K9 demethylation
GO:0035064 methylated histone binding
GO:0045666 positive regulation of neuron differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048712 negative regulation of astrocyte differentiation
GO:0051864 histone demethylase activity (H3-K36 specific)
GO:0060548 negative regulation of cell death
GO:0070544 histone H3-K36 demethylation
GO:1900113 negative regulation of histone H3-K9 trimethylation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR002999 Tudor domainDomainDomain
IPR003347 JmjC domainDomainDomain
IPR003349 JmjN domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR034732 Extended PHD (ePHD) domainDomainDomain
IPR040477 Lysine-specific demethylase 4, Tudor domainDomainDomain

Diseases

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Interactions

3 interactions