Entity Details

Primary name KPCD2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BZ03
EntryNameKPCD2_MOUSE
FullNameSerine/threonine-protein kinase D2
TaxID10090
Evidenceevidence at protein level
Length875
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesPrkd2

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002250 adaptive immune response
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004698 calcium-dependent protein kinase C activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0007155 cell adhesion
GO:0008219 cell death
GO:0010595 positive regulation of endothelial cell migration
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032743 positive regulation of interleukin-2 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032793 positive regulation of CREB transcription factor activity
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0035556 intracellular signal transduction
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway
GO:0045766 positive regulation of angiogenesis
GO:0045785 positive regulation of cell adhesion
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0050852 T cell receptor signaling pathway
GO:0050862 positive regulation of T cell receptor signaling pathway
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0089700 protein kinase D signaling
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901727 positive regulation of histone deacetylase activity
GO:1902533 positive regulation of intracellular signal transduction
GO:2000573 positive regulation of DNA biosynthetic process
GO:2001028 positive regulation of endothelial cell chemotaxis

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR015727 Protein kinase C mu-relatedFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020454 Diacylglycerol/phorbol-ester bindingDomainDomain

Diseases

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Interactions

0 interactions

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