Entity Details

Primary name ASXL2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BZ32
EntryNameASXL2_MOUSE
FullNamePutative Polycomb group protein ASXL2
TaxID10090
Evidenceevidence at protein level
Length1370
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesAsxl2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003007 heart morphogenesis
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006351 transcription, DNA-templated
GO:0007507 heart development
GO:0007512 adult heart development
GO:0009887 animal organ morphogenesis
GO:0010884 positive regulation of lipid storage
GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0035517 PR-DUB complex
GO:0042975 peroxisome proliferator activated receptor binding
GO:0045600 positive regulation of fat cell differentiation
GO:0045672 positive regulation of osteoclast differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048704 embryonic skeletal system morphogenesis
GO:1900159 positive regulation of bone mineralization involved in bone maturation
GO:1902466 positive regulation of histone H3-K27 trimethylation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR007759 ASXL, HARE-HTH domainDomainDomain
IPR024811 Polycomb protein ASX/ASX-likeFamilyFamily
IPR024817 ASX-like protein 2FamilyFamily
IPR026905 Protein ASX-like, PHD domainDomainDomain
IPR028020 ASX, DEUBAD domainDomainDomain

Diseases

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Interactions

3 interactions