Entity Details

Primary name KCNH2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO35219
EntryNameKCNH2_MOUSE
FullNamePotassium voltage-gated channel subfamily H member 2
TaxID10090
Evidenceevidence at protein level
Length1162
SequenceStatuscomplete
DateCreated2002-11-28
DateModified2021-06-02

Ontological Relatives

GenesKcnh2

GO terms

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GOName
GO:0005216 ion channel activity
GO:0005242 inward rectifier potassium channel activity
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005267 potassium channel activity
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006813 potassium ion transport
GO:0008076 voltage-gated potassium channel complex
GO:0009986 cell surface
GO:0031625 ubiquitin protein ligase binding
GO:0035690 cellular response to drug
GO:0042391 regulation of membrane potential
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044877 protein-containing complex binding
GO:0048471 perinuclear region of cytoplasm
GO:0055075 potassium ion homeostasis
GO:0055131 C3HC4-type RING finger domain binding
GO:0060048 cardiac muscle contraction
GO:0060306 regulation of membrane repolarization
GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
GO:0071805 potassium ion transmembrane transport
GO:0086005 ventricular cardiac muscle cell action potential
GO:0086009 membrane repolarization
GO:0086010 membrane depolarization during action potential
GO:0086011 membrane repolarization during action potential
GO:0086013 membrane repolarization during cardiac muscle cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:0097110 scaffold protein binding
GO:0097623 potassium ion export across plasma membrane
GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential
GO:1901379 regulation of potassium ion transmembrane transport
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:1901381 positive regulation of potassium ion transmembrane transport
GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
GO:1902937 inward rectifier potassium channel complex
GO:1903765 negative regulation of potassium ion export across plasma membrane
GO:1990573 potassium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR000595 Cyclic nucleotide-binding domainDomainDomain
IPR000700 PAS-associated, C-terminalDomainDomain
IPR001610 PAC motifRepeatRepeat
IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERGFamilyFamily
IPR003967 Potassium channel, voltage-dependent, ERGFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR014710 RmlC-like jelly roll foldFamilyHomologous superfamily
IPR018490 Cyclic nucleotide-binding-likeFamilyHomologous superfamily
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR035965 PAS domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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