Entity Details

Primary name SH3R2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BZT2
EntryNameSH3R2_MOUSE
FullNameE3 ubiquitin-protein ligase SH3RF2
TaxID10090
Evidenceevidence at protein level
Length735
SequenceStatuscomplete
DateCreated2006-12-12
DateModified2021-06-02

Ontological Relatives

GenesSh3rf2

GO terms

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GOName
GO:0004864 protein phosphatase inhibitor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0008157 protein phosphatase 1 binding
GO:0010923 negative regulation of phosphatase activity
GO:0019902 phosphatase binding
GO:0030335 positive regulation of cell migration
GO:0031397 negative regulation of protein ubiquitination
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043066 negative regulation of apoptotic process
GO:0046329 negative regulation of JNK cascade
GO:0046330 positive regulation of JNK cascade
GO:0046872 metal ion binding
GO:0051865 protein autoubiquitination
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR018957 Zinc finger, C3HC4 RING-typeDomainDomain
IPR028511 E3 ubiquitin-protein ligase SH3RF2FamilyFamily
IPR035792 E3 ubiquitin-protein ligase SH3RF2, first SH3 domainDomainDomain
IPR035794 E3 ubiquitin-protein ligase SH3RF2, second SH3 domainDomainDomain
IPR035822 SH3RF2, third SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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