Entity Details

Primary name WWP1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BZZ3
EntryNameWWP1_MOUSE
FullNameNEDD4-like E3 ubiquitin-protein ligase WWP1
TaxID10090
Evidenceevidence at protein level
Length918
SequenceStatuscomplete
DateCreated2003-06-20
DateModified2021-06-02

Ontological Relatives

GenesWwp1

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016567 protein ubiquitination
GO:0030217 T cell differentiation
GO:0030324 lung development
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045732 positive regulation of protein catabolic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR000569 HECT domainDomainDomain
IPR001202 WW domainDomainDomain
IPR024928 E3 ubiquitin-protein ligase, SMURF1 typeFamilyFamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR035983 HECT, E3 ligase catalytic domainFamilyHomologous superfamily
IPR036020 WW domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
WWP1_MOUSEHXD12_MOUSEBioGRID, IntAct20211142 details
WWP1_MOUSETRAF6_MOUSEBioGRID23799152 details
WWP1_MOUSEWBP1L_MOUSEBioGRID31845480 details