Entity Details

Primary name E2F3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO35261
EntryNameE2F3_MOUSE
FullNameTranscription factor E2F3
TaxID10090
Evidenceevidence at protein level
Length457
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesE2f3

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001216 DNA-binding transcription activator activity
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006606 protein import into nucleus
GO:0008284 positive regulation of cell population proliferation
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0070345 negative regulation of fat cell proliferation
GO:0090575 RNA polymerase II transcription regulator complex
GO:1905461 positive regulation of vascular associated smooth muscle cell apoptotic process
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003316 E2F/DP family, winged-helix DNA-binding domainDomainDomain
IPR015633 E2F FamilyFamilyFamily
IPR032198 E2F transcription factor, CC-MB domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037241 E2F-DP heterodimerization regionFamilyHomologous superfamily

Diseases

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Interactions

3 interactions