Entity Details

Primary name HDAC7_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8C2B3
EntryNameHDAC7_MOUSE
FullNameHistone deacetylase 7
TaxID10090
Evidenceevidence at protein level
Length938
SequenceStatuscomplete
DateCreated2003-05-16
DateModified2021-06-02

Ontological Relatives

GenesHdac7

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001570 vasculogenesis
GO:0003682 chromatin binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005080 protein kinase C binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006325 chromatin organization
GO:0006476 protein deacetylation
GO:0006954 inflammatory response
GO:0007043 cell-cell junction assembly
GO:0007399 nervous system development
GO:0008134 transcription factor binding
GO:0019901 protein kinase binding
GO:0030183 B cell differentiation
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032703 negative regulation of interleukin-2 production
GO:0033558 protein deacetylase activity
GO:0042113 B cell activation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045843 negative regulation of striated muscle tissue development
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0071889 14-3-3 protein binding
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:1901215 negative regulation of neuron death
GO:1901223 negative regulation of NIK/NF-kappaB signaling

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000286 Histone deacetylase familyFamilyFamily
IPR017320 Histone deacetylase class II, eukaryoticFamilyFamily
IPR023696 Ureohydrolase domain superfamilyFamilyHomologous superfamily
IPR023801 Histone deacetylase domainDomainDomain
IPR033660 Histone deacetylase 4/7FamilyFamily
IPR037138 Histone deacetylase domain superfamilyFamilyHomologous superfamily

Diseases

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