Entity Details

Primary name CRBN_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8C7D2
EntryNameCRBN_MOUSE
FullNameProtein cereblon
TaxID10090
Evidenceevidence at protein level
Length445
SequenceStatuscomplete
DateCreated2005-08-30
DateModified2021-06-02

Ontological Relatives

GenesCrbn

GO terms

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GOName
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016567 protein ubiquitination
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex
GO:0034766 negative regulation of ion transmembrane transport
GO:0035641 locomotory exploration behavior
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044325 transmembrane transporter binding
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:1902607 negative regulation of large conductance calcium-activated potassium channel activity

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR003111 Lon, substrate-binding domainDomainDomain
IPR004910 Yippee/Mis18/CereblonDomainDomain
IPR015947 PUA-like superfamilyFamilyHomologous superfamily
IPR034750 CULT domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CRBN_MOUSEA4_MOUSEBioGRID27325702 details
CRBN_MOUSERABX5_MOUSEBioGRID27601648 details