Entity Details

Primary name APH1B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8C7N7
EntryNameAPH1B_MOUSE
FullNameGamma-secretase subunit APH-1B
TaxID10090
Evidenceevidence at transcript level
Length257
SequenceStatuscomplete
DateCreated2003-09-26
DateModified2021-06-02

Ontological Relatives

GenesAph1b

GO terms

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GOName
GO:0001963 synaptic transmission, dopaminergic
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006509 membrane protein ectodomain proteolysis
GO:0007219 Notch signaling pathway
GO:0007220 Notch receptor processing
GO:0007614 short-term memory
GO:0010950 positive regulation of endopeptidase activity
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0030133 transport vesicle
GO:0030674 protein-macromolecule adaptor activity
GO:0034205 amyloid-beta formation
GO:0035249 synaptic transmission, glutamatergic
GO:0042987 amyloid precursor protein catabolic process
GO:0045202 synapse
GO:0060134 prepulse inhibition
GO:0061133 endopeptidase activator activity
GO:0070765 gamma-secretase complex

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR009294 Gamma-secretase subunit Aph-1FamilyFamily

Diseases

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