Entity Details

Primary name MRP1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO35379
EntryNameMRP1_MOUSE
FullNameMultidrug resistance-associated protein 1
TaxID10090
Evidenceevidence at protein level
Length1528
SequenceStatuscomplete
DateCreated2004-09-27
DateModified2021-06-02

Ontological Relatives

GenesAbcc1

GO terms

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GOName
GO:0005324 long-chain fatty acid transporter activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006979 response to oxidative stress
GO:0008559 ABC-type xenobiotic transporter activity
GO:0009925 basal plasma membrane
GO:0015431 ABC-type glutathione S-conjugate transporter activity
GO:0015562 efflux transmembrane transporter activity
GO:0015911 long-chain fatty acid import across plasma membrane
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0016887 ATP hydrolysis activity
GO:0030335 positive regulation of cell migration
GO:0033700 phospholipid efflux
GO:0034040 ATPase-coupled lipid transmembrane transporter activity
GO:0034634 glutathione transmembrane transporter activity
GO:0034775 glutathione transmembrane transport
GO:0042493 response to drug
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042887 amide transmembrane transporter activity
GO:0042908 xenobiotic transport
GO:0042910 xenobiotic transmembrane transporter activity
GO:0045332 phospholipid translocation
GO:0046943 carboxylic acid transmembrane transporter activity
GO:0050729 positive regulation of inflammatory response
GO:0055085 transmembrane transport
GO:0060326 cell chemotaxis
GO:0060548 negative regulation of cell death
GO:0070633 transepithelial transport
GO:0071716 leukotriene transport
GO:0099039 sphingolipid translocation
GO:0140115 export across plasma membrane
GO:0140359 ABC-type transporter activity
GO:1901215 negative regulation of neuron death
GO:1904646 cellular response to amyloid-beta
GO:1905039 carboxylic acid transmembrane transport
GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR005292 Multi drug resistance-associated proteinFamilyFamily
IPR011527 ABC transporter type 1, transmembrane domainDomainDomain
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036640 ABC transporter type 1, transmembrane domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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