Entity Details

Primary name CACB2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8CC27
EntryNameCACB2_MOUSE
FullNameVoltage-dependent L-type calcium channel subunit beta-2
TaxID10090
Evidenceevidence at protein level
Length655
SequenceStatuscomplete
DateCreated2004-07-05
DateModified2021-06-02

Ontological Relatives

GenesCacnb2

GO terms

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GOName
GO:0005245 voltage-gated calcium channel activity
GO:0005246 calcium channel regulator activity
GO:0005886 plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0007268 chemical synaptic transmission
GO:0007528 neuromuscular junction development
GO:0007601 visual perception
GO:0008331 high voltage-gated calcium channel activity
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0042802 identical protein binding
GO:0051015 actin filament binding
GO:0051219 phosphoprotein binding
GO:0051928 positive regulation of calcium ion transport
GO:0070509 calcium ion import
GO:0072659 protein localization to plasma membrane
GO:0086045 membrane depolarization during AV node cell action potential
GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:0098684 photoreceptor ribbon synapse
GO:0098793 presynapse
GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential
GO:0099635 voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
GO:1901385 regulation of voltage-gated calcium channel activity
GO:1901843 positive regulation of high voltage-gated calcium channel activity
GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
GO:1990454 L-type voltage-gated calcium channel complex

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000584 Voltage-dependent calcium channel, L-type, beta subunitFamilyFamily
IPR001452 SH3 domainDomainDomain
IPR005444 Voltage-dependent calcium channel, L-type, beta-2 subunitFamilyFamily
IPR008145 Guanylate kinase/L-type calcium channel beta subunitDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035605 CACNB2, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CACB2_MOUSECAC1A_MOUSEBioGRID16787652 32325033 details
CACB2_MOUSECAC1B_MOUSEBioGRID16787652 32325033 details