Entity Details

Primary name H2AW_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8CCK0
EntryNameH2AW_MOUSE
FullNameCore histone macro-H2A.2
TaxID10090
Evidenceevidence at protein level
Length372
SequenceStatuscomplete
DateCreated2006-03-21
DateModified2021-06-02

Ontological Relatives

GenesMacroh2a2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000786 nucleosome
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001740 Barr body
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006334 nucleosome assembly
GO:0006342 chromatin silencing
GO:0007420 brain development
GO:0007549 dosage compensation
GO:0031490 chromatin DNA binding
GO:0045618 positive regulation of keratinocyte differentiation
GO:0045814 negative regulation of gene expression, epigenetic
GO:0046982 protein heterodimerization activity
GO:0071169 establishment of protein localization to chromatin
GO:1901837 negative regulation of transcription of nucleolar large rRNA by RNA polymerase I

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR002119 Histone H2AFamilyFamily
IPR002589 Macro domainDomainDomain
IPR007125 Histone H2A/H2B/H3DomainDomain
IPR009072 Histone-foldFamilyHomologous superfamily
IPR021171 Core histone macro-H2AFamilyFamily
IPR032454 Histone H2A, C-terminal domainDomainDomain
IPR035796 Core histone macro-H2A, macro domainDomainDomain
IPR043472 Macro domain-likeFamilyHomologous superfamily

Diseases

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Interactions

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