Entity Details

Primary name ERCC8_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8CFD5
EntryNameERCC8_MOUSE
FullNameDNA excision repair protein ERCC-8
TaxID10090
Evidenceevidence at protein level
Length397
SequenceStatuscomplete
DateCreated2005-06-07
DateModified2021-06-02

Ontological Relatives

GenesErcc8

GO terms

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GOName
GO:0000012 single strand break repair
GO:0000109 nucleotide-excision repair complex
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006289 nucleotide-excision repair
GO:0006974 cellular response to DNA damage stimulus
GO:0006979 response to oxidative stress
GO:0009411 response to UV
GO:0010165 response to X-ray
GO:0010996 response to auditory stimulus
GO:0014070 response to organic cyclic compound
GO:0016363 nuclear matrix
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex
GO:0032991 protein-containing complex
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043204 perikaryon
GO:0044877 protein-containing complex binding
GO:0045739 positive regulation of DNA repair
GO:0051865 protein autoubiquitination
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
GO:0097680 double-strand break repair via classical nonhomologous end joining

Subcellular Location

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Subcellular Location
Nucleus
Nucleus matrix

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily
IPR042238 DNA excision repair protein Rad28/ERCC8/Ckn1/ATCSA-1FamilyFamily

Diseases

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