Entity Details

Primary name NED4L_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8CFI0
EntryNameNED4L_MOUSE
FullNameE3 ubiquitin-protein ligase NEDD4-like
TaxID10090
Evidenceevidence at protein level
Length1004
SequenceStatuscomplete
DateCreated2005-08-30
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0003085 negative regulation of systemic arterial blood pressure
GO:0003254 regulation of membrane depolarization
GO:0004842 ubiquitin-protein transferase activity
GO:0005737 cytoplasm
GO:0005771 multivesicular body
GO:0005794 Golgi apparatus
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006513 protein monoubiquitination
GO:0009651 response to salt stress
GO:0010038 response to metal ion
GO:0010765 positive regulation of sodium ion transport
GO:0010766 negative regulation of sodium ion transport
GO:0015459 potassium channel regulator activity
GO:0016567 protein ubiquitination
GO:0017080 sodium channel regulator activity
GO:0019870 potassium channel inhibitor activity
GO:0019871 sodium channel inhibitor activity
GO:0030154 cell differentiation
GO:0031647 regulation of protein stability
GO:0034765 regulation of ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044325 transmembrane transporter binding
GO:0045732 positive regulation of protein catabolic process
GO:0048814 regulation of dendrite morphogenesis
GO:0060306 regulation of membrane repolarization
GO:0061630 ubiquitin protein ligase activity
GO:0070936 protein K48-linked ubiquitination
GO:0086005 ventricular cardiac muscle cell action potential
GO:1901016 regulation of potassium ion transmembrane transporter activity
GO:1901017 negative regulation of potassium ion transmembrane transporter activity
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:1902306 negative regulation of sodium ion transmembrane transport
GO:1903861 positive regulation of dendrite extension
GO:2000009 negative regulation of protein localization to cell surface
GO:2000650 negative regulation of sodium ion transmembrane transporter activity
GO:2000810 regulation of bicellular tight junction assembly
GO:2001259 positive regulation of cation channel activity
GO:2001288 positive regulation of caveolin-mediated endocytosis

Subcellular Location

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Subcellular Location
Cytoplasm
Endosome
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR000569 HECT domainDomainDomain
IPR001202 WW domainDomainDomain
IPR024928 E3 ubiquitin-protein ligase, SMURF1 typeFamilyFamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR035983 HECT, E3 ligase catalytic domainFamilyHomologous superfamily
IPR036020 WW domain superfamilyFamilyHomologous superfamily

Diseases

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