Entity Details

Primary name SEM6A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO35464
EntryNameSEM6A_MOUSE
FullNameSemaphorin-6A
TaxID10090
Evidenceevidence at protein level
Length1031
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesSema6a

GO terms

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GOName
GO:0001755 neural crest cell migration
GO:0001764 neuron migration
GO:0004888 transmembrane signaling receptor activity
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006915 apoptotic process
GO:0007166 cell surface receptor signaling pathway
GO:0007411 axon guidance
GO:0016020 membrane
GO:0016525 negative regulation of angiogenesis
GO:0030215 semaphorin receptor binding
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0042802 identical protein binding
GO:0045499 chemorepellent activity
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0050919 negative chemotaxis
GO:0051642 centrosome localization
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071526 semaphorin-plexin signaling pathway
GO:0106089 negative regulation of cell adhesion involved in sprouting angiogenesis
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
GO:1903671 negative regulation of sprouting angiogenesis
GO:2001224 positive regulation of neuron migration

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001627 Sema domainDomainDomain
IPR002165 Plexin repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR027231 SemaphorinFamilyFamily
IPR036352 Sema domain superfamilyFamilyHomologous superfamily

Diseases

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