Entity Details

Primary name NGEF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8CHT1
EntryNameNGEF_MOUSE
FullNameEphexin-1
TaxID10090
Evidenceevidence at protein level
Length710
SequenceStatuscomplete
DateCreated2006-09-05
DateModified2021-06-02

Ontological Relatives

GenesNgef

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0007399 nervous system development
GO:0009987 cellular process
GO:0016020 membrane
GO:0030154 cell differentiation
GO:0030426 growth cone
GO:0043087 regulation of GTPase activity
GO:0046875 ephrin receptor binding
GO:0048013 ephrin receptor signaling pathway
GO:0061002 negative regulation of dendritic spine morphogenesis
GO:0090630 activation of GTPase activity
GO:0098883 synapse pruning
GO:0098978 glutamatergic synapse

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035635 Ephexin-1, SH3 domainDomainDomain
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NGEF_MOUSEEPHA4_MOUSEIntAct21029865 details