Entity Details

Primary name NOX1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8CIZ9
EntryNameNOX1_MOUSE
FullNameNADPH oxidase 1
TaxID10090
Evidenceevidence at protein level
Length591
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesNox1

GO terms

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GOName
GO:0000302 response to reactive oxygen species
GO:0001525 angiogenesis
GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0006952 defense response
GO:0007165 signal transduction
GO:0008284 positive regulation of cell population proliferation
GO:0010575 positive regulation of vascular endothelial growth factor production
GO:0016174 NAD(P)H oxidase H2O2-forming activity
GO:0016175 superoxide-generating NAD(P)H oxidase activity
GO:0016477 cell migration
GO:0030054 cell junction
GO:0030198 extracellular matrix organization
GO:0031267 small GTPase binding
GO:0042554 superoxide anion generation
GO:0042743 hydrogen peroxide metabolic process
GO:0042995 cell projection
GO:0043020 NADPH oxidase complex
GO:0043410 positive regulation of MAPK cascade
GO:0045726 positive regulation of integrin biosynthetic process
GO:0046330 positive regulation of JNK cascade
GO:0046872 metal ion binding
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0051454 intracellular pH elevation
GO:0071455 cellular response to hyperoxia
GO:0072592 oxygen metabolic process
GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1990451 cellular stress response to acidic pH
GO:2000379 positive regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000778 Cytochrome b245, heavy chainFamilyFamily
IPR013112 FAD-binding 8DomainDomain
IPR013121 Ferric reductase, NAD binding domainDomainDomain
IPR013130 Ferric reductase transmembrane component-like domainDomainDomain
IPR017927 FAD-binding domain, ferredoxin reductase-typeDomainDomain
IPR017938 Riboflavin synthase-like beta-barrelFamilyHomologous superfamily
IPR029650 NADPH oxidase 1FamilyFamily
IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domainFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink