Entity Details

Primary name ASPM_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8CJ27
EntryNameASPM_MOUSE
FullNameAbnormal spindle-like microcephaly-associated protein homolog
TaxID10090
Evidenceevidence at protein level
Length3122
SequenceStatuscomplete
DateCreated2004-07-05
DateModified2021-06-02

Ontological Relatives

GenesAspm

GO terms

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GOName
GO:0000922 spindle pole
GO:0001764 neuron migration
GO:0002052 positive regulation of neuroblast proliferation
GO:0005516 calmodulin binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005874 microtubule
GO:0007051 spindle organization
GO:0007283 spermatogenesis
GO:0007420 brain development
GO:0008584 male gonad development
GO:0016324 apical plasma membrane
GO:0021873 forebrain neuroblast division
GO:0021987 cerebral cortex development
GO:0030496 midbody
GO:0036449 microtubule minus-end
GO:0045665 negative regulation of neuron differentiation
GO:0045769 negative regulation of asymmetric cell division
GO:0048477 oogenesis
GO:0048589 developmental growth
GO:0051445 regulation of meiotic cell cycle
GO:0051653 spindle localization
GO:0051661 maintenance of centrosome location
GO:0072687 meiotic spindle
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0090306 meiotic spindle assembly
GO:0097150 neuronal stem cell population maintenance
GO:0097431 mitotic spindle pole

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR001715 Calponin homology domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR029955 Abnormal spindle-like microcephaly-associated proteinFamilyFamily
IPR031549 Abnormal spindle-like microcephaly-associated protein, ASH domainDomainDomain
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ASPM_MOUSEOTUD4_HUMANBioGRID31138677 details