Entity Details

Primary name AGO4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8CJF8
EntryNameAGO4_MOUSE
FullNameProtein argonaute-4
TaxID10090
Evidenceevidence at transcript level
Length861
SequenceStatuscomplete
DateCreated2003-11-14
DateModified2021-06-02

Ontological Relatives

GenesAgo4

GO terms

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GOName
GO:0000932 P-body
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006402 mRNA catabolic process
GO:0007130 synaptonemal complex assembly
GO:0007140 male meiotic nuclear division
GO:0008584 male gonad development
GO:0010501 RNA secondary structure unwinding
GO:0010586 miRNA metabolic process
GO:0016442 RISC complex
GO:0022604 regulation of cell morphogenesis
GO:0031054 pre-miRNA processing
GO:0035196 production of miRNAs involved in gene silencing by miRNA
GO:0035198 miRNA binding
GO:0035278 miRNA mediated inhibition of translation
GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0043066 negative regulation of apoptotic process
GO:0070578 RISC-loading complex

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR003100 PAZ domainDomainDomain
IPR003165 Piwi domainDomainDomain
IPR012337 Ribonuclease H-like superfamilyFamilyHomologous superfamily
IPR014811 Argonaute, linker 1 domainDomainDomain
IPR028604 Protein argonaute-4FamilyFamily
IPR032472 Argonaute linker 2 domainDomainDomain
IPR032473 Protein argonaute, Mid domainDomainDomain
IPR032474 Protein argonaute, N-terminalDomainDomain
IPR036085 PAZ domain superfamilyFamilyHomologous superfamily
IPR036397 Ribonuclease H superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AGO4_MOUSEOTUD4_HUMANBioGRID31138677 details