Entity Details

Primary name AKC1H_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8K023
EntryNameAKC1H_MOUSE
FullNameAldo-keto reductase family 1 member C18
TaxID10090
Evidenceevidence at protein level
Length323
SequenceStatuscomplete
DateCreated2005-06-07
DateModified2021-06-02

Ontological Relatives

GenesAkr1c18

GO terms

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GOName
GO:0001758 retinal dehydrogenase activity
GO:0004032 alditol:NADP+ 1-oxidoreductase activity
GO:0004033 aldo-keto reductase (NADP) activity
GO:0004745 NAD-retinol dehydrogenase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006693 prostaglandin metabolic process
GO:0006709 progesterone catabolic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007565 female pregnancy
GO:0007567 parturition
GO:0008202 steroid metabolic process
GO:0008284 positive regulation of cell population proliferation
GO:0010942 positive regulation of cell death
GO:0016229 steroid dehydrogenase activity
GO:0016488 farnesol catabolic process
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018636 phenanthrene 9,10-monooxygenase activity
GO:0032052 bile acid binding
GO:0034614 cellular response to reactive oxygen species
GO:0035410 dihydrotestosterone 17-beta-dehydrogenase activity
GO:0042448 progesterone metabolic process
GO:0042574 retinal metabolic process
GO:0044597 daunorubicin metabolic process
GO:0044598 doxorubicin metabolic process
GO:0045550 geranylgeranyl reductase activity
GO:0045703 ketoreductase activity
GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
GO:0047023 androsterone dehydrogenase activity
GO:0047086 ketosteroid monooxygenase activity
GO:0047787 delta4-3-oxosteroid 5beta-reductase activity
GO:0047834 D-threo-aldose 1-dehydrogenase activity
GO:0048385 regulation of retinoic acid receptor signaling pathway
GO:0050810 regulation of steroid biosynthetic process
GO:0051897 positive regulation of protein kinase B signaling
GO:0061370 testosterone biosynthetic process
GO:0071276 cellular response to cadmium ion
GO:0071277 cellular response to calcium ion
GO:0071372 cellular response to follicle-stimulating hormone stimulus
GO:0071379 cellular response to prostaglandin stimulus
GO:0071384 cellular response to corticosteroid stimulus
GO:0071394 cellular response to testosterone stimulus
GO:0071395 cellular response to jasmonic acid stimulus
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0071799 cellular response to prostaglandin D stimulus
GO:0097211 cellular response to gonadotropin-releasing hormone
GO:1900053 negative regulation of retinoic acid biosynthetic process
GO:1904322 cellular response to forskolin
GO:1990646 cellular response to prolactin
GO:2000224 regulation of testosterone biosynthetic process
GO:2000353 positive regulation of endothelial cell apoptotic process
GO:2000379 positive regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR018170 Aldo/keto reductase, conserved siteSiteConserved site
IPR020471 Aldo-keto reductaseFamilyFamily
IPR023210 NADP-dependent oxidoreductase domainDomainDomain
IPR036812 NADP-dependent oxidoreductase domain superfamilyFamilyHomologous superfamily
IPR044482 Aldo-keto reductase family 1 member CFamilyFamily

Diseases

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Interactions

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