Entity Details

Primary name DNM1L_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8K1M6
EntryNameDNM1L_MOUSE
FullNameDynamin-1-like protein
TaxID10090
Evidenceevidence at protein level
Length742
SequenceStatuscomplete
DateCreated2005-05-10
DateModified2021-06-02

Ontological Relatives

GenesDnm1l

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000266 mitochondrial fission
GO:0001836 release of cytochrome c from mitochondria
GO:0003374 dynamin family protein polymerization involved in mitochondrial fission
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005777 peroxisome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005903 brush border
GO:0005905 clathrin-coated pit
GO:0006816 calcium ion transport
GO:0007005 mitochondrion organization
GO:0008017 microtubule binding
GO:0008289 lipid binding
GO:0010468 regulation of gene expression
GO:0010637 negative regulation of mitochondrial fusion
GO:0010821 regulation of mitochondrion organization
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0016559 peroxisome fission
GO:0030276 clathrin binding
GO:0030672 synaptic vesicle membrane
GO:0030742 GTP-dependent protein binding
GO:0031267 small GTPase binding
GO:0031625 ubiquitin protein ligase binding
GO:0031966 mitochondrial membrane
GO:0032991 protein-containing complex
GO:0036466 synaptic vesicle recycling via endosome
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043653 mitochondrial fragmentation involved in apoptotic process
GO:0044877 protein-containing complex binding
GO:0048312 intracellular distribution of mitochondria
GO:0048471 perinuclear region of cytoplasm
GO:0048488 synaptic vesicle endocytosis
GO:0048511 rhythmic process
GO:0050714 positive regulation of protein secretion
GO:0051259 protein complex oligomerization
GO:0051433 BH2 domain binding
GO:0060047 heart contraction
GO:0061003 positive regulation of dendritic spine morphogenesis
GO:0061025 membrane fusion
GO:0065003 protein-containing complex assembly
GO:0070266 necroptotic process
GO:0070584 mitochondrion morphogenesis
GO:0070585 protein localization to mitochondrion
GO:0090023 positive regulation of neutrophil chemotaxis
GO:0090141 positive regulation of mitochondrial fission
GO:0090149 mitochondrial membrane fission
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0090650 cellular response to oxygen-glucose deprivation
GO:0098835 presynaptic endocytic zone membrane
GO:0099073 mitochondrion-derived vesicle
GO:0099503 secretory vesicle
GO:1900063 regulation of peroxisome organization
GO:1900244 positive regulation of synaptic vesicle endocytosis
GO:1903146 regulation of autophagy of mitochondrion
GO:1903578 regulation of ATP metabolic process
GO:1904579 cellular response to thapsigargin
GO:1904666 regulation of ubiquitin protein ligase activity
GO:1905395 response to flavonoid
GO:1990910 response to hypobaric hypoxia
GO:2000302 positive regulation of synaptic vesicle exocytosis
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle
Endomembrane system
Golgi apparatus
Membrane
Mitochondrion outer membrane
Peroxisome

Domains

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DomainNameCategoryType
IPR000375 Dynamin stalk domainDomainDomain
IPR001401 Dynamin, GTPase domainDomainDomain
IPR003130 Dynamin GTPase effectorDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR019762 Dynamin, GTPase region, conserved siteSiteConserved site
IPR020850 GTPase effector domainDomainDomain
IPR022812 DynaminFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030381 Dynamin-type guanine nucleotide-binding (G) domainDomainDomain
IPR030556 Dynamin-1-like proteinFamilyFamily

Diseases

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