Entity Details

Primary name I5P2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8K337
EntryNameI5P2_MOUSE
FullNameType II inositol 1,4,5-trisphosphate 5-phosphatase
TaxID10090
Evidenceevidence at protein level
Length993
SequenceStatuscomplete
DateCreated2012-01-25
DateModified2021-06-02

Ontological Relatives

GenesInpp5b

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004445 inositol-polyphosphate 5-phosphatase activity
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0007283 spermatogenesis
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030317 flagellated sperm motility
GO:0030670 phagocytic vesicle membrane
GO:0031901 early endosome membrane
GO:0046855 inositol phosphate dephosphorylation
GO:0046856 phosphatidylinositol dephosphorylation
GO:0046872 metal ion binding
GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0070613 regulation of protein processing

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle
Early endosome membrane
Endoplasmic reticulum-Golgi intermediate compartment
Membrane

Domains

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DomainNameCategoryType
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR000300 Inositol polyphosphate-related phosphataseDomainDomain
IPR005135 Endonuclease/exonuclease/phosphataseDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR031896 INPP5B, PH domainDomainDomain
IPR036691 Endonuclease/exonuclease/phosphatase superfamilyFamilyHomologous superfamily
IPR037793 OCRL1/INPP5B, INPP5c domainDomainDomain

Diseases

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Interactions

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