Entity Details

Primary name GLP1R_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO35659
EntryNameGLP1R_MOUSE
FullNameGlucagon-like peptide 1 receptor
TaxID10090
Evidenceevidence at protein level
Length463
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesGlp1r

GO terms

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GOName
GO:0001653 peptide receptor activity
GO:0004967 glucagon receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007218 neuropeptide signaling pathway
GO:0007611 learning or memory
GO:0007613 memory
GO:0007631 feeding behavior
GO:0008016 regulation of heart contraction
GO:0008284 positive regulation of cell population proliferation
GO:0008306 associative learning
GO:0008528 G protein-coupled peptide receptor activity
GO:0009749 response to glucose
GO:0017046 peptide hormone binding
GO:0019933 cAMP-mediated signaling
GO:0030073 insulin secretion
GO:0032024 positive regulation of insulin secretion
GO:0038023 signaling receptor activity
GO:0043066 negative regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0044508 glucagon-like peptide 1 receptor activity
GO:0045597 positive regulation of cell differentiation
GO:0045777 positive regulation of blood pressure
GO:0045823 positive regulation of heart contraction
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046879 hormone secretion
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051924 regulation of calcium ion transport
GO:1990911 response to psychosocial stress

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001879 GPCR, family 2, extracellular hormone receptor domainDomainDomain
IPR003290 GPCR, family 2, glucagon-like peptide-1/glucagon receptorFamilyFamily
IPR003292 GPCR, family 2, glucagon-like peptide-1 receptorFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR017983 GPCR, family 2, secretin-like, conserved siteSiteConserved site
IPR036445 GPCR family 2, extracellular hormone receptor domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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