Entity Details

Primary name TRIB3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8K4K2
EntryNameTRIB3_MOUSE
FullNameTribbles homolog 3
TaxID10090
Evidenceevidence at protein level
Length354
SequenceStatuscomplete
DateCreated2003-02-01
DateModified2021-06-02

Ontological Relatives

GenesTrib3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003714 transcription corepressor activity
GO:0004860 protein kinase inhibitor activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006468 protein phosphorylation
GO:0006469 negative regulation of protein kinase activity
GO:0010506 regulation of autophagy
GO:0010827 regulation of glucose transmembrane transport
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0031625 ubiquitin protein ligase binding
GO:0032092 positive regulation of protein binding
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032869 cellular response to insulin stimulus
GO:0034976 response to endoplasmic reticulum stress
GO:0043405 regulation of MAP kinase activity
GO:0045599 negative regulation of fat cell differentiation
GO:0045717 negative regulation of fatty acid biosynthetic process
GO:0045732 positive regulation of protein catabolic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0051443 positive regulation of ubiquitin-protein transferase activity
GO:0055106 ubiquitin-protein transferase regulator activity
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR024104 Pseudokinase tribbles family/serine-threonine-protein kinase 40FamilyFamily
IPR024106 Pseudokinase tribbles, TRB3FamilyFamily

Diseases

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